[{"namespace":"cellular_component","parents":[{"definition":"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.","namespace":"cellular_component","ontology":"GO","subsets":["goslim_agr","goslim_chembl","goslim_euk_cellular_processes_ribbon","goslim_flybase_ribbon","goslim_mouse","goslim_pir"],"name":"protein-containing complex","synonyms":["macromolecular complex","macromolecule complex","protein containing complex","protein complex","protein-protein complex"],"accession":"GO:0032991"}],"subsets":["goslim_pir"],"accession":"GO:0005667","definition":"A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.","ontology":"GO","synonyms":["cytoplasmic transcription factor complex","nuclear transcription factor complex","transcription factor complex"],"name":"transcription regulator complex","children":[{"name":"RNA polymerase II transcription regulator complex","synonyms":["RNA polymerase II transcription factor complex"],"subsets":[],"accession":"GO:0090575","namespace":"cellular_component","ontology":"GO","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II."},{"namespace":"cellular_component","ontology":"GO","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.","accession":"GO:0000120","subsets":[],"synonyms":["RNA polymerase I transcription factor complex"],"name":"RNA polymerase I transcription regulator complex"},{"accession":"GO:0090576","name":"RNA polymerase III transcription regulator complex","synonyms":["RNA polymerase III transcription factor complex"],"subsets":[],"ontology":"GO","namespace":"cellular_component","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III."},{"namespace":"cellular_component","definition":"A protein complex that possesses activity that prevents or downregulates transcription.","ontology":"GO","accession":"GO:0017053","synonyms":["transcription factor inhibitor complex","transcriptional repressor complex","cytoplasmic transcriptional repressor complex","nuclear transcriptional repressor complex"],"name":"transcription repressor complex","subsets":["goslim_pir"]},{"ontology":"GO","namespace":"cellular_component","definition":"A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.","accession":"GO:0019185","name":"snRNA-activating protein complex","synonyms":["SNAPc"],"subsets":[]},{"name":"Cbf1-Met4-Met28 complex","synonyms":[],"subsets":[],"accession":"GO:0089713","definition":"A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.","namespace":"cellular_component","ontology":"GO"},{"synonyms":["RNA polymerase IV transcription factor complex"],"name":"RNA polymerase IV transcription regulator complex","subsets":[],"accession":"GO:0090577","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.","namespace":"cellular_component","ontology":"GO"},{"accession":"GO:0090578","subsets":[],"name":"RNA polymerase V transcription regulator complex","synonyms":["RNA polymerase V transcription factor complex"],"definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.","namespace":"cellular_component","ontology":"GO"},{"accession":"GO:1903865","synonyms":[],"name":"sigma factor antagonist complex","subsets":[],"namespace":"cellular_component","definition":"A protein complex which is capable of sigma factor antagonist activity.","ontology":"GO"},{"namespace":"cellular_component","definition":"A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.","ontology":"GO","subsets":[],"name":"ModE complex","synonyms":["ModE dimer"],"accession":"GO:1990198"},{"definition":"A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.","namespace":"cellular_component","ontology":"GO","subsets":[],"name":"CHOP-ATF3 complex","synonyms":["ATF3-CHOP complex","CHOP-ATF3 heterodimer","CHOP-ATF3 heterodimeric complex","GADD153-ATF3 complex"],"accession":"GO:1990622"},{"ontology":"GO","namespace":"cellular_component","definition":"An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.","accession":"GO:0016581","synonyms":["NRD complex","nucleosome remodeling and histone deacetylation complex","Mi-2 complex"],"name":"NuRD complex","subsets":[]}]}]